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KMID : 0387720230340010021
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Korean Journal of Blood Transfusion
2023 Volume.34 No. 1 p.21 ~ p.25
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Effectiveness of Malaria Antibody Test for Screening Blood Donors
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Kang Jung-Won
Kim Jae-Hyun
Lee Jae-Sook
Ko Deuk-Yeong
Kim Hwang-Min
Choi Kyoung-Young
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Abstract
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The Republic of Korea has been using malaria antibody assays to screen blood donors and reduce the risk of transfusion-transmitted malaria (TTM). This study examined the effectiveness of the current malaria antibody test for screening blood donors and calculated the positive predictive value (PPV) with the real-time polymerase chain reaction (RT-PCR) as the reference. The reactive rate and PPV of the malaria antibody screening assay during particular period from 2020 to 2021 were 0.82% (248/30,309) and 0.40% (1/248), respectively. The low PPV of current malaria antibody screening in blood donors suggests that the effectiveness of this test is limited in terms of balancing blood safety and supply in low-prevalence situations.
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KEYWORD
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Transfusion-transmitted malaria, Antibody screening, Real-time PCR, Effectiveness
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